Vague symptoms which are worrying, please use the Non Site-Specific pathway on ICE.

Non-specific pain and abdo symptoms:

• Lasted more than 3 weeks
• Lasted less than 6 months
• Malignancy suspected within differential diagnosis
• No red flag symptoms

Non-specific weight loss/appetite loss symptoms:

• Recent and unexplained
• > 5% weight loss
• Not previously investigated
• No likely benign diagnosis
• No red flag symptoms

Patients presenting with suspected metastatic malignancy on diagnostic imaging with undefined primary and no red flag symptoms or signs to direct to site specific clinic – refer to Malignancy of Undefined Origin (CUP)

For further GP guidance, consider using crhft.imaging-secs@nhs.net.

If tests abnormal, then please refer the patient to the appropriate site specific 2WW pathway: e.g. abnormal chest x-ray to Lung 2WW Pathway, iron def anaemia to Upper GI 2WW Pathway, etc.